Oral route of administration is most common and preferred method of delivery due to its convenience and ease of ingestion. BCS class II drugs are poorly water soluble drug with low aqueous solubility and high permeability, such drugs exhibit dissolution rate limited absorption resulting in poor bioavailability of drug when deliver through oral route. Solid dispersion is very efficient technique to increase the bioavailability and dissolution rate of poorly soluble drug. This article reviews background of solid dispersion, classification, advantages, disadvantages, selection of solvents and carriers. It also reviews characterization and method of preparation of solid dispersion.
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